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15 August 2017

Effective testosterone treatment reduces incidence of atrial fibrillation

Effective testosterone treatment reduces incidence of atrial fibrillation

Sharma, R., et al., Normalization of Testosterone Levels After Testosterone Replacement Therapy Is Associated With Decreased Incidence of Atrial Fibrillation. J Am Heart Assoc, 2017. 6(5)

While the effect of testosterone treatment on heart disease is a topic of ongoing debate, a growing body of evidence is refuting the widespread belief that testosterone treatment supposedly is harmful in terms of heart disease risk.

Here we report the results of a study, published in the Journal of the American Heart Association, which investigated the effect of testosterone treatment on the incidence of atrial fibrillation - an irregular and often rapid heart rate that can increase risk of stroke, heart failure and other heart-related complications - in testosterone deficient men with documented low testosterone levels.

Key Points

  • Atrial fibrillation is the most common form of abnormal heart rhythm, causing significant morbidity, mortality, and financial burden, especially in older men.
  • Effective testosterone treatment that achieves large enough elevations in testosterone levels reduces the incidence of atrial fibrillation by up to 21%.
  • Ineffective testosterone treatment, which does not achieve large enough elevations in testosterone levels, does not confer benefits.

Last updated: 2019
G.MKT.GM.MH.02.2018.0506