Hypogonadism (testosterone deficiency)

Male hypogonadism is a clinical syndrome resulting from a failure of the testes to produce physiological levels of testosterone (androgen deficiency), sperm, or both, because of disruption of one or more levels of the hypothalamic-pituitary-gonadal axis.

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Testosterone tools

Try out our four helpful Testosterone Tools. They make it much easier to manage the treatment of hypogonadism. These tools allow for easy testosterone conversion and free testosterone calculation, provide an algorithm for diagnosis and treatment of hypogonadism, and a visualization of when each of the many beneficial testosterone effects can be expected to manifest.

Testosterone therapy

The essential aim of testosterone therapy is to restore serum testosterone to the middle of the normal physiological range and to minimize the signs and symptoms of hypogonadism.

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Treatment guidelines


Guidelines and recommendations issued by medical societies on the definition, investigation, treatment and follow-up of men with late-onset hypogonadism.

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References

  • Dohle et al. EAU Guidelines. 2018: Arnhern, the Netherlands. Return to content
  • Kumar et al. J Adv Pharm Technol Res. 2010 Jul-Sep: 1(3): 297-301). Return to content
  • T raish AM. Outcomes of testosterone therapy in men with testosterone deficiency (TD): Part II. Steroids. 2014;88C:117-126. Return to content
  • Wittert G, Bracken K, Robledo KP, et al. Testosterone treatment to prevent or revert type 2 diabetes in men enrolled in a lifestyle programme (T4DM): a randomised, double-blind, placebo-controlled, 2-year, phase 3b trial. The Lancet Diabetes & Endocrinology. Jan 2021;9(1):32-45. Return to content