Should testosterone treatment be used in asymptomatic men with low testosterone?


Prof. Wittert’s position on this issue is; no. Prof. Wittert argues that this implies screening for low testosterone in the absence of symptoms, for which there is no logic. What are these men presenting with? Prof. Wittert presents a patient case and data on the burden of undiagnosed disease in men, to illustrate his position.

Prof. Wittert concludes that currently there are no clinical data to support the use of testosterone therapy in asymptomatic men with low testosterone. He points out that men take note of erectile dysfunction and nocturia, which is cheap to screen for and improve with lifestyle change.



Prof. Dr. med. Marija Pfeifer

Prof. Gary Wittert

Freemasons Foundation Centre for Men's Health University of Adelaide, Australia


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  • Jones TH, Saad F. The effects of testosterone on risk factors for, and the mediators of, the atherosclerotic process. Atherosclerosis. 2009 Dec;207(2):318-27 Return to content