There have been concerns regarding a possible increased incidence of DVT and pulmonary embolism (PE) with testosterone therapy. However, few data support the association between testosterone therapy and DVT/PE. In another study, Dr Barua’s group evaluated the incidence of DVT and PE in men who were prescribed testosterone therapy for low testosterone levels.3 This was a large study including 71,407 subjects with low baseline testosterone and low to moderate baseline risk of DVT/PE. After a follow-up of 14 years, there was no significant association between testosterone therapy and risk of DVT/PE.3