Weight Loss vs. testosterone therapy


Obese men commonly have low testosterone levels and report symptoms consistent with androgen deficiency. Dr. Teo presents his clinical experience with obese men. While acknowledging that a large weight loss increases testosterone levels, the degree of weight loss necessary is hard to achieve and even harder to maintain. Furthermore, the increases are not large enough to provide symptomatic improvement in obese men.1 A study that specifically investigated whether testosterone treatment improves symptoms over and above the effects of weight loss alone, concluded that in obese men with mild to moderate symptoms and modest reductions in testosterone levels, testosterone treatment improved testosterone deficiency symptoms over and above the improvement associated with weight loss alone, and more severely symptomatic men achieved a greater benefit.

Dr. Teo receives non-compliant patient referrals from diabetes clinics that he puts on testosterone therapy. He says testosterone therapy makes patients follow the treatment rules.



Prof. Dr. med. Marija Pfeifer

Dr. Colin Teo
Head of Urology Department, Khoo Teck Puat Hospital
President, Society for Men’s Health, Singapore


  • Ng Tang Fui M, Hoermann R, Prendergast LA, Zajac JD, Grossmann M. Symptomatic response to testosterone treatment in dieting obese men with low testosterone levels in a randomized, placebo-controlled clinical trial. Int J Obes (Lond). 2017 Mar;41(3):420-426 Return to content