The benefits of testosterone replacement on sexual function, fat and lean body mass, blood lipids and bone density in men with low testosterone are clear. The potential benefits of testosterone replacement in reducing the risk of cardiovascular disease, metabolic syndrome and diabetes are still being investigated.
Health and well-being – quality of life
Improvements in signs and symptoms of low testosterone, such as libido, sexual, physical and mental functioning and mood, can be expected over time and will show you that the treatment is working.
Testosterone replacement in men with low testosterone increases lean body mass and strength and decreases fat mass.
Current evidence suggests that testosterone replacement in men is relatively safe in terms of cardiovascular health and does not cause important cardiovascular side effects. Indeed, there is some evidence that testosterone replacement is beneficial for cardiovascular disease and may continue to improve cardiovascular risk factors over time. Evidence is emerging that testosterone may protect against clogging or hardening of the arteries (atherosclerosis).
Testosterone therapy may also have metabolic benefits in men with diabetes and/or metabolic syndrome. Men with diabetes have been shown to have substantially lower testosterone levels than men in the general population, yet low testosterone in many remains undiagnosed and untreated. It is not yet fully known whether diabetes is a cause or a consequence of low testosterone. However, some studies have shown testosterone replacement therapy has a beneficial effect on risk factors for diabetes such as central obesity, insulin sensitivity, glucose control and blood lipid profiles in men with low testosterone.
Low testosterone can lead to thinning of the bones (osteoporosis) and men with hip fractures tend to have low testosterone. Testosterone replacement increases bone density.
If low testosterone occurs during adulthood, you can make some lifestyle and dietary changes to help prevent osteoporosis. Regular exercise and adequate amounts of calcium and vitamin D help to maintain bone strength and are important to reduce the risk of osteoporosis.