June 2013
Arterial stiffness contributes to cardiovascular conditions that can increase the risk of mortality. Sex hormones have been suggested to play a role in vascular function and in this study the elastic properties of the aorta (the largest artery in the body) in men with low blood levels of testosterone (hypogonadism) were compared with those of a control group who naturally produce normal levels of testosterone.
Impaired aortic elastic properties in patients with adult-onset hypogonadism.
Canpolat U, Tokgözoğlu L, Aydin K, Dural M, Gϋrses KM, Yorgun H, et al. Blood Press 2013;22:114–9.
It is known that low testosterone levels in men are strongly associated with a number of conditions including obesity, diabetes, metabolic syndrome, vascular disease and arterial stiffness. Furthermore, testosterone has also been shown to influence a number of mechanisms that contribute to age-related dysfunction of the lining of arteries. There is also evidence that stiffness in large arteries independently predicts cardiovascular morbidity and mortality. However, few studies had previously investigated the association between testosterone blood levels and arterial stiffness.