Cardiometabolic
symptoms / signs
- Obesity (BMI 30 or higher)
- Abdominal (belly) obesity (waist circumference 102 cm or higher)
- Metabolic syndrome
- Insulin resistance, prediabetes or type 2 diabetes
Sexual symptoms
- Small testes
- Infertility
- Decreased sexual desire and activity
- Decreased frequency of sexual thoughts
- Erectile dysfunction
- Delayed ejaculation
- Decreased volume of ejaculate
- Decreased frequency or absent morning or night-time erections

Psychological symptoms
- Irritability
- Sadness
- Depressive symptoms
- Loss of energy
- Reduced motivation
- Poor concentration
- Impaired memory
- Decreased well-being and/or poor self-rated health
- Decreased cognitive function (including impaired concentration, verbal memory, and spatial performance)
Physical symptoms
- Decreased body hair
- Gynecomastia (female breasts)
- Decreased muscle mass and strength
- Reduced physical performance
- Hot flushes or sweats
- Sleep disturbances
- Fatigue
- Reduced bone mineral density, osteoporosis, low trauma fractures